Phytochemical Screening and Albumin Induced Anti-Inflammatory Activity of Pentas Lanceolata Leaves | Zendy

P. Kura | Zendy; Anita K. Patlolla | Zendy; Ramesh Alluri | Zendy; Vishwanadham Yerragunta | Zendy

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Phytochemical Screening and Albumin Induced Anti-Inflammatory Activity of Pentas Lanceolata Leaves

Author(s) -

P. Kura,

Anita K. Patlolla,

Ramesh Alluri,

Vishwanadham Yerragunta

Publication year - 2018

Publication title -

pharmatutor

Language(s) - English

Resource type - Journals

eISSN - 2394-6679

pISSN - 2347-7881

DOI - 10.29161/pt.v6.i3.2018.27

Subject(s) - phytochemical , terpenoid , diclofenac , chemistry , glycoside , traditional medicine , petroleum ether , flavonoid , anti inflammatory , albumin , pharmacology , saline , medicine , biochemistry , chromatography , stereochemistry , antioxidant , anesthesia , extraction (chemistry)

The anti-inflammatory drug activity of petroleum ether (Pet.ether) extract of leaves pentas lanceolata was investigated in rat’s exploitation egg albumen induced paw oedema model. Experimental animals received 20-25 gms (orally) of the extracts five groups divided., control group (saline), test group 50, 100, 200 mg/ kg the standard group received 15 mg/ kg of diclofenac. The results show that the extracts considerably (p <0.05) reduced paw oedema within the albumen induced anti-inflammatory drug activity. The leaf extract of pentas lanceolata reduced inflamed hind paw diameter of mice by between 0.98%- 3.99% The diclofenac reduced inflamed hind paw diameter by between 1.12%-4.02%. The qualitative phytochemical screening indicated the presence of saponins, flavonoid, alkaloids, terpenoids and cardiac glycosides. The current study establishes potent antiinflammatory activities of pet ether extracts of pentas lanceolata leaves.

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