A Review on Chalcones Synthesis and their Biological Activity
Author(s) -
Sunil Verma,
Ruchi Srivastava,
O. P. Pandey
Publication year - 2018
Publication title -
pharmatutor
Language(s) - English
Resource type - Journals
eISSN - 2394-6679
pISSN - 2347-7881
DOI - 10.29161/pt.v6.i2.2018.22
Subject(s) - chalcone , antimicrobial , biological activity , chemistry , flavonoid , antioxidant , combinatorial chemistry , traditional medicine , organic chemistry , biochemistry , medicine , in vitro
Chalcones are a valuable molecule of medicinal importance due to presence of reactive ketoethylenic group –CO–CH=CH–, belonging to the flavonoid family. These reactive α,β-unsatutated keto function in chalcones are responsible for their biological activity. Chalcone can be synthesized by several methods using aldehydes and ketones as starting material. This review is focused about different methods of synthesis and versatile biological activity of chalcones including antimicrobial, anticancer, antioxidant, antimalarial, antituberculosis etc.
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