Open AccessEffect of Iles-Iles (Amorphophallus oncophyllus) Synbiotic Effervescent Tablet to Decrease in Blood Sugar Levels in Hyperglycemic White Rat (Rattus norvegicus)
Author(s) -
Ngatirah Ngatirah,
Meidi Syaflan,
Satria A. N
Publication year - 2020
Publication title -
digital press life sciences
Language(s) - English
Resource type - Journals
ISSN - 2654-9441
DOI - 10.29037/digitalpress.22330
Subject(s) - blood sugar , sugar , medicine , body weight , dose dependence , traditional medicine , food science , chemistry , endocrinology , diabetes mellitus
This study aims to determine the effect of giving Iles-iles synbiotic effervescent tablets to decrease blood sugar levels of hyperglycemic white rats and find out the lowest dose of effervescent tablets in decreasing blood sugar levels. This study used the Completely Randomized Design (CRD) with single factor (dose of Iles-iles synbiotic effervescent tablet) with 4 levels (dose 0.045 gram/day (½ normal dose), dose 0.09 gram/day (normal dose), dose 0.18 gram/day (2X normal dose) and Control (without treatment dose). The analysis carried out was blood sugar levels and rat body weight. The administration of Iles-iles synbiotic effervescent tablets can reduce blood sugar levels in white mice but does not affect changes in the weight of white mice. The biggest decrease in blood sugar levels in white rats for synbiotic month was obtained from the administration of a dose of 0.18 grams/day (normal 2X dose) which was as much as 49.16% The administration of effervescent tablets in the fourth week with a normal dose of 0.09 grams/200 grams of weight has been able to reduce blood sugar levels in white rats to normal levels.