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Aim: Deep vein thrombosis (DVT) is a prevailing cause of serious complications such as pulmonary thromboembolism, venous ulcer, chronic venous insufficiency, venous gangrene and postthrombotic syndrome, and significantly increased hospitalization costs. The aim of this study is to determine the incidence of DVT and regional effects for its development as well as evaluate its distribution in terms of age and gender in Yozgat, a city with a population of more than 500.000 people, which is considered to fairly represent Central Anatolia with regards to geography, economy, industry, age distribution, morbidity and mortality.  Methods: For this cross-sectional study, we included all DVT cases aged 15 years and older from Yozgat diagnosed in Bozok University, Faculty of Medicine, Research and Application Hospital and Yozgat State Hospital between September 2012-September 2016. Patients and diagnostic characteristics were retrieved from medical records. The distribution of DVT cases were evaluated in terms of age and gender according to the data derived from address-based population registration system of Turkish Statistical Institute (TUSI) 2016. Results: One thousand two hundred and eighty-seven patients were enrolled in this research. DVT incidence increased with age and substantially accelerated above the age of 40. The overall DVT incidence was 1:1000 persons per year and slightly higher among the female population (1:1000 persons/year vs 0.9:1000 persons/year) (P=0.924). According to TUSI 2016, the mean body mass index (BMI) of females was significantly higher than that of males (29.2 (5.3) kg/m² and 26.7 (3.6) kg/m², respectively, P<0.001). In the region comprising Yozgat, Sivas and Kayseri, labor-force participation rate of females and males were 28% and 49.6%, respectively, which was a significant regional risk factor for DVT development.  Conclusion: It would be possible to decrease the incidence of DVT and the high hospitalization costs of related complications, most of which can be avoided with suitable prophylaxis based on more reliable results obtained from further research. Appropriate precautions should be taken after considering regional socioeconomic and sociocultural values.

Evaluation of deep vein thrombosis incidence with respect to age and gender in light of regional factors in central Anatolia: A population-based study