Living donor liver transplantation in hepatocellular carcinoma: A single-center experiences | Zendy

Gökhan Ertuğrul | Zendy; Tümay Uludağ Yanaral | Zendy

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Living donor liver transplantation in hepatocellular carcinoma: A single-center experiences

Author(s) -

Gökhan Ertuğrul,

Tümay Uludağ Yanaral

Publication year - 2019

Publication title -

journal of surgery and medicine

Language(s) - Turkish

Resource type - Journals

ISSN - 2602-2079

DOI - 10.28982/josam.557019

Subject(s) - hepatocellular carcinoma , medicine , liver transplantation , milan criteria , gastroenterology , hepatitis b virus , transplantation , carcinoma , hepatitis c , living donor liver transplantation , hepatitis c virus , hepatitis b , virus , immunology

Amac: Hepatosellur karsinom ( HCC ) karacigerin en sik gorulen primer solid tumorudur. Hepatit B virus (HBV) enfeksiyonlari, hepatit C virus ( HCV ) enfeksiyonlari veya alkolizm zemininde de gorulebilir. Bu calismanin amaci, HCC nedeniyle canli vericili karaciger nakli yapilan hastalarin degerlendirilmesidir. Yontemler: Retrospektif kohort calisma planlandi. Nisan 2014 – Aralik 2017 tarihleri arasinda Medipol Universitesi Tip Fakultesi, Organ Nakli Merkezi'nde HCC nedeniyle canli vericili karaciger nakli yapilan 38 hasta degerlendirildi. Bulgular: Ortalama yas 58,0 (9,9) (20-74) yildi; 38 kisiden 31'i (%81,6) erkekti. Ortalama MELD skoru 14,2 (8–32) idi. Milan kriterleri disinda (P=0,003), kotu farklilasmis ve kolanjiokarsinom tumor bileseni (P=0,003), olan hepatoselluler karsinomda canli vericili karaciger naklinde daha kotu gorunmektedir. Sonuclar: Bu calismada Milan disi, az differansiye ve kolanjiokarsinom komponenti olan tumorlerin daha kotu oldugu gorunmektedir.

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