Genetically Encoded Neural Activity Indicators | Zendy

Fang Luo | Zendy; Yin Wei | Zendy; Ziyue Wang | Zendy; Minmin Luo | Zendy; Ji Hu | Zendy

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Genetically Encoded Neural Activity Indicators

Author(s) -

Fang Luo,

Yin Wei,

Ziyue Wang,

Minmin Luo,

Ji Hu

Publication year - 2018

Publication title -

brain science advances

Language(s) - English

Resource type - Journals

ISSN - 2096-5958

DOI - 10.26599/bsa.2018.9050007

Subject(s) - neural activity , computer science , computational biology , genetically engineered , neuroscience , biology , artificial intelligence , gene , biochemistry

Recent years have witnessed the fascinating development of imaging approaches to studying neural activities; this progress has been based on an influx of ideas and methods from molecular biology and optical engineering. Here we review the design and application of genetically encoded indicators for calcium ions, membrane potential and neurotransmitters. We also summarize common strategies for the design and optimization of genetically encoded neural activity indicators.

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