A study on understanding the blood lipid profile of the hemodialysis patients in Al-Diwaniyah Province, Iraq
Author(s) -
Shaymaa Rabeea Madhkhoor,
Jameel K. Alumeri
Publication year - 2019
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v10i4.1613
Subject(s) - hemodialysis , medicine , triglyceride , cholesterol , dialysis , chronic renal failure , lipid profile , endocrinology , blood lipids , lipoprotein , low density lipoprotein
One of themost frequentlyworldwide recorded health conditions, is a chronic renal failure (CRF), especially in elderly individuals induced due to renal damage. Kidney damage and therefore, dialysis have several detrimental effects on the body organs and their functions. According to those effects, this studywas conducted to recognize the blood lipid pro ile of the hemodialysis patients in Al-Diwaniyah Province, Iraq. Such determination gives assurance for overall functions of the body organs in order to place proper medical management of those levels if disturbed. From Al-Diwaniyah General Teaching Hospital, Diwaniyah City, Iraq, 68 (50, 33 males and 17 females, hemodialysis CRF (HCRF) patients and 18, 11 males and 7 females, healthy individuals) samples of blood were collected. For revealing the levels of serum blood lipids of the participants, total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were tested using a cholesterol oxidase method for TC and HDL-C, a glycerol kinase method for TG, and the Friedewald formula for LDL-C. The results unveiled signi icant (p< 0.01) higher TG levels in H-CRF patients than those in healthy individuals. In addition, HDL-C revealed signi icant (p< 0.01) lower levels in the H-CRF patients than those in healthy people. No signi icant (p> 0.01) data were observed from the TC and the LDL-C levels in both groups. This work demonstrates the level changes of the TGs and the HDL-C in the serum of the hemodialysis patients which need propermedical intervention for the correction of those levels.
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