Challenging Received Wisdom: Antidepressants and the Placebo Effect | Zendy

Irving Kirsch | Zendy

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Challenging Received Wisdom: Antidepressants and the Placebo Effect

Author(s) -

Irving Kirsch

Publication year - 2020

Publication title -

mcgill journal of medicine

Language(s) - English

Resource type - Journals

eISSN - 1715-8125

pISSN - 1201-026X

DOI - 10.26443/mjm.v11i2.571

Subject(s) - placebo , medicine , denial , antidepressant , clinical trial , placebo response , psychiatry , alternative medicine , psychotherapist , intensive care medicine , psychology , anxiety , pathology

This article explores the reaction when an article challenging received wisdom is published and covered extensively by the media (1). The article in question was a meta-analysis of antidepressant clinical trials indicating that for most patients, difference between drug and placebo was not clinically significant. Reactions ranged from denial that the effects of antidepressants are so small to criticisms of the clinical trials that were analyzed. Each of these reactions is explored and countered.

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