The effectiveness of zofenopril in patients with cardiovascular disease
Author(s) -
V G Kukes,
G S Anikin
Publication year - 2014
Publication title -
systemic hypertension
Language(s) - English
Resource type - Journals
eISSN - 2542-2189
pISSN - 2075-082X
DOI - 10.26442/sg29028
Subject(s) - renin–angiotensin system , disease , medicine , pharmacology , angiotensin converting enzyme , aldosterone , blood pressure
Hyperactivity of the renin-angiotensin-aldosterone system plays an important role in the pathogenesis of any cardiovascular disease. Angiotensin - converting enzyme inhibitors are the main drugs among many medicines influencing the activity of the renin-angiotensin-aldosterone system, and these inhibitors have a wide range of beneficial effects. The presence of the sulfhydryl group in a molecule of angiotensin-converting enzyme inhibitor (zofenopril) determines the number of unique properties of this drug. Recent results have been showing the effectiveness of treatment in case of combined cardiovascular disease. This article presents the results of the studies showing the efficacy and safety of zofenopril.
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