Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes
Author(s) -
Xiaojiang Xie,
Agustín Gutiérrez,
Valentin Trofimov,
István Szilágyi,
Thierry Soldati,
Eric Bakker
Publication year - 2015
Publication title -
chimia international journal for chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2015.196
Subject(s) - nanosensor , dictyostelium discoideum , ionophore , nanotechnology , amoeba (genus) , potassium , intracellular , chemistry , biophysics , materials science , biochemistry , biology , microbiology and biotechnology , organic chemistry , membrane , gene
lonophore-based ion-selective optical nanosensors have been explored for a number of years. Voltage sensitive dyes (VSDs) have been introduced into this type of sensors only very recently, forming a new class of analytical tools. Here, K(+)-sensitive nanospheres incorporating a lipophilic VSD were successfully fabricated and characterized. The nanosensors were readily delivered into the social amoeba Dictyostelium discoideum in a non-invasive manner, forming a promising new platform for intracellular ion quantification and imaging.
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