Cyclodextrin-based Combinatorial Polymers: Efficient Binders of Pharmaceuticals in Water
Author(s) -
Patrick Shahgaldian,
Philippe F.-X. Corvini
Publication year - 2013
Publication title -
chimia international journal for chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2013.425
Subject(s) - polymer , cyclodextrin , sorbent , chemistry , nanomaterials , combinatorial chemistry , organic chemistry , chemical engineering , materials science , nanotechnology , adsorption , engineering
Cyclodextrins are cyclic oligomers of glucose; they are widely used in a large range of industrial applications because of their molecular inclusion properties. We used cyclodextrins to prepare different libraries of polymers and tested their ability to selectively recognize pharmaceuticals in water. It was demonstrated that the chemical composition of the polymer strongly influences its binding properties. The developed strategy can be used to produce selective sorbent nanomaterials of pharmaceuticals.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom