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Allergy is a widespread immunological disorder often related with Western lifestyles in which sterile environments deprive the immune system of factors stimulating its proper development. Allergic diseases, for example allergic rhinitis and asthma, are mediated by histamine (and other substances) released from mast cells due to their interaction with special type of antibody, so-called IgE antibodies, in response to normally harmless substances, allergens. IgE antibodies recognize allergens and activate mast cells, thus a high level (>200 µg/L for adults) of IgE in blood serum is an allergy indicator.

Allergy Diagnostics Using Magnetic Beads in a GRAVITM-Cell Microfluidic Device