Identification of Dioxin Metabolites in the Poisoning Case of Victor Yushchenko
Author(s) -
Markus Zennegg,
Olivier Sorg,
Peter Schmid,
JeanHilaire Saurat
Publication year - 2010
Publication title -
chimia international journal for chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.387
H-Index - 55
eISSN - 2673-2424
pISSN - 0009-4293
DOI - 10.2533/chimia.2010.95
Subject(s) - urine , adipose tissue , sweat , population , physiology , feces , chemistry , toxicology , medicine , endocrinology , biology , environmental health , microbiology and biotechnology
In autumn 2004, the current Ukrainian president, Victor Yushchenko, suffered a severe dioxin poisoning. First blood serum levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), measured in December 2004, were 110’000 pg/g lipid weight. These blood serum levels were more than 50’000 times higher than those in the general population and represent the second highest ever measured concentrations of TCDD in a human. We monitored the levels of TCDD and its metabolites for more than three years in various samples of blood serum, adipose tissue, skin, urine, faeces, and sweat of Victor Yushchenko. The work was only possible thanks to the cooperation and expressed consent of Victor Yushchenko
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