An Efficient Entry to Planar Chiral Organometallic Complexes via Pd-Catalyzed Asymmetric Hydrogenolysis | Zendy

Audrey Mercier | Zendy; Wee Chuan Yeo | Zendy; Xavier Urbaneja | Zendy; E. Peter Kündig | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

An Efficient Entry to Planar Chiral Organometallic Complexes via Pd-Catalyzed Asymmetric Hydrogenolysis

Author(s) -

Audrey Mercier,

Wee Chuan Yeo,

Xavier Urbaneja,

E. Peter Kündig

Publication year - 2010

Publication title -

chimia international journal for chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.387

H-Index - 55

eISSN - 2673-2424

pISSN - 0009-4293

DOI - 10.2533/chimia.2010.177

Subject(s) - hydrogenolysis , kinetic resolution , chemistry , phosphoramidite , catalysis , reagent , ligand (biochemistry) , stereocenter , ruthenium , asymmetric hydrogenation , combinatorial chemistry , borane , organometallic chemistry , enantioselective synthesis , photochemistry , organic chemistry , dna , biochemistry , receptor , oligonucleotide

Planar chiral chromium- and ruthenium-based arene complexes were prepared with high levels of enantioselectivity via a Pd-catalyzed asymmetric hydrogenolysis reaction using a bulky chiral phosphoramidite ligand. Key elements for the efficiency of the process are the use of DABCO as borane-trapping reagent as well as substantial kinetic resolution, which was found to enhance the stereochemical outcome of the reaction.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research