Transmeatal Low Level Laser Therapy (LLLT) on Vestibular Inner Ear after Topical Gentamicin Ototoxicity

Materials and Methods We measured penetration rate of transmeatal low level laser (LLL) into the perilymphatic space of cochlea through a tympanic membrane, cochlea wall and hearing level post transmeatal LLLT were measured. Histopathologic studies on ear canal skin and ear drum were performed for observation of any damage by LLLT. Guinea pigs were then divided into control and LLLT group. Both groups received injection of gentamicin (GM) into the left middle ear. LLLT group were irradiated into the left ear through the external ear canal for 5 days starting 1 day after GM injection into the left ear. The animals underwent sinusoidal oscillation about a vertical and off vertical axis 5 days post GM injection.