Anti-p200 pemphigoid: A review | Zendy

Vattiyamveetil Sajeela Rasheed | Zendy

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Anti-p200 pemphigoid: A review

Author(s) -

Vattiyamveetil Sajeela Rasheed

Publication year - 2021

Publication title -

journal of skin and sexually transmitted diseases

Language(s) - English

Resource type - Journals

eISSN - 2994-6026

pISSN - 2582-3175

DOI - 10.25259/jsstd_35_2021

Subject(s) - pemphigoid , autoantibody , blisters , bullous pemphigoid , medicine , dermatology , immunology , autoimmune disease , p200 , disease , pathology , antibody , psychology , perception , visual perception , neuroscience

Anti-p200 pemphigoid, initially described in 1996, is a subepidermal autoimmune blistering disease. It is manifested as tense blisters, mostly in an acral distribution, and is accompanied by mucosal involvement in more than half the cases. The disease is produced by circulating autoantibodies directed against the dermal antigen of 200-kDa, the exact identity of which remains unknown. This review focuses on the clinical features, immunopathogenesis, and diagnosis of anti-p200 pemphigoid.

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