Histopathological study of dermal granuloma

The granulomatous reaction pattern is defined as a distinctive inflammatory pattern characterized by the granulomas.[1] It is difficult to present a completely satisfactory classification of granulomatous reaction.[2] Granulomatous lesions of skin and subcutaneous tissue are known as “Dermal Granulomas,” which are of four types; immunogenic, infectious, foreign body, and granulomas associated with tissue injury.[3] Skin biopsies and microscopic study with routine hematoxylin and eosin as well as by special stains are must to identify the type and etiologic agent of the granuloma. In present study, following types of dermal granulomas were included–leprosy, cutaneous tuberculosis, syphilis, fungal, actinomycosis, foreign body granuloma, granuloma annulare, and sarcoidosis.