GC-MS Analysis of Momordica charantia and Momordica dioica Fruit and Root Methanolic Extracts

The present paper reports the GC-MS analysis studies of Momordica charantia and Momordica dioica Fruit and Rootmethanolic extracts. An attempt is made to analyze comparatively for the presence of similar compounds with biologicalactivity in both the plants, to assess the chemotaxonomic relationship between these two plants. These two plants areperennial, rhizomatous, climbers belonging to cucurbitaceae family. These are seasonal vegetables of high demand andmedicinal plants in Asian countries. Momordica charantia is indigenous and because of its higher medicinal importance itis also cultivated throughout the world. There is a growing demand for fruit and roots of Momordica charantia andMomordica dioica in the pharmaceutical trade due to their usage as medicinal agents for anti-inflammation, degenerativediseases including atherosclerosis, ischemic heart disease, ageing, diabetes mellitus, cancer, neurodegenerative diseasesand others. In the present study fruit and roots of Momordica charantia and Momordica dioica were sequentially extractedby methanol and GC-MS analysis is carried for the extracts separately. The extracts showed the presence of manyphytoconstituents reported in these plants. The GC-MS analysis of the methanolic extract revealed the presence of manysimilar major compound like plamictic acid with antidiabetic property is identified in both fruit and root methanolic extractsof Momordica charantia and Momordica dioica . This study forms a basis for the biological characterization andimportance of the compounds identified.