Effects of Misuse of Antibiotics on the Resistance of Escherichia coli Isolated from the Intestines of Broiler Chickens

The coliform bacteria is one of the most important bacterial diseases that threaten the poultry sector in Iraq, and the result of the excessive and indiscriminate use of antibiotics during the farming period to eliminate coliform bacteria has led to the development of antibiotics resistance. The current study aimed to investigate the Escherichia coli in the poultry intestines and to determine its ability to resist antibiotics to achieve this, 177 samples of poultry intestines were collected from local poultry farming houses in Babil province included 142 isolates (80.22%) of E. coli and 35 isolates (19.77%) for other intestinal bacteria. In this study, the bacterial susceptibility test for E. coli showed a significant difference at a statistical level of p < 0.05 by chi-square method for the antibiotics resistance ratios, respectively, rifampicin (100%), oxytetracycline (99.29%), cefixime (98.59%), sulfamethoxazole + trimethoprim (95.77%), norfloxacin (90.14%), cefepime (89.43%), nitrofurantoin (72.53%), gentamicin (71.12%), ceftazidime (70%). Also, Indian ink was used to detect the presence of the capsule around the E. coli, where the results of the microscopic examination showed 81 isolates (57.04%) were surrounded by the capsule and 61 isolates, 42.95% were not surrounded. Finally, the study concluded that the bacterial resistance of E. coli continues to rise and is alarming and is threatening public health. Keyword: Broilers gut, Escherichia coli, Misuse of antibiotics, Resistance. International Journal of Drug Delivery Technology (2020); DOI: 10.25258/ijddt.10.2.1 How to cite this article: Abed AR, Khudhair AM, Hussein IM. Effects of Misuse of antibiotics on the resistance of Escherichia coli isolated from the intestines of broiler chickens. International Journal of Drug Delivery Technology. 2020;10(2):190-194. Source of support: Nil Conflict of interest: None Effects of Misuse of Antibiotics on the Resistance of Escherichia coli Isolated from the Intestines of Broiler Chickens Abbas Razzaq Abed*, Aleem Mardas Khudhair, Ibtisam Mohammed Hussein Technical Institute of Babylon, Al-Furat Al-Awsat Technical University, Babylon, Iraq Received: 12th March, 2020; Revised: 27th April, 2020; Accepted: 16th May, 2020; Available Online: 25th June, 2020