Open AccessBDNF Val66Met Polymorphism Is Related to Motor System Function After Stroke
Author(s) -
Dae Yul Kim,
Erin Burke Quinlan,
Robert Gramer,
Steven C. Cramer
Publication year - 2015
Publication title -
physical therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 150
eISSN - 1538-6724
pISSN - 0031-9023
DOI - 10.2522/ptj.20150135
Subject(s) - motor function , medicine , physical medicine and rehabilitation , stroke (engine) , polymorphism (computer science) , cardiology , genetics , biology , genotype , physics , gene , thermodynamics
The val(66)met polymorphism in brain-derived neurotrophic factor (BDNF) has been associated with poorer outcomes after stroke. The mechanism for this finding remains uncertain but might be related to the reduced motor system activation associated with this polymorphism in healthy people.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom