Muscle Atrophy, Voluntary Activation Disturbances, and Low Serum Concentrations of IGF-1 and IGFBP-3 Are Associated With Weakness in People With Chronic Stroke | Zendy

Marcela de Abreu Silva-Couto | Zendy; Christiane L. Prado-Medeiros | Zendy; Ana Beatriz Oliveira | Zendy; Carolina Carmona Alcântara | Zendy; Araci Teixeira Guimarães | Zendy; Tânia F. Salvini | Zendy; Rosana Mattioli | Zendy; Thiago Luiz Russo | Zendy

Open Access

Muscle Atrophy, Voluntary Activation Disturbances, and Low Serum Concentrations of IGF-1 and IGFBP-3 Are Associated With Weakness in People With Chronic Stroke

Author(s) -

Marcela de Abreu Silva-Couto,

Christiane L. Prado-Medeiros,

Ana Beatriz Oliveira,

Carolina Carmona Alcântara,

Araci Teixeira Guimarães,

Tânia F. Salvini,

Rosana Mattioli,

Thiago Luiz Russo

Publication year - 2014

Publication title -

physical therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.998

H-Index - 150

eISSN - 1538-6724

pISSN - 0031-9023

DOI - 10.2522/ptj.20130322

Subject(s) - biceps , medicine , muscle atrophy , muscle weakness , weakness , atrophy , electromyography , physical medicine and rehabilitation , hemiparesis , skeletal muscle , endocrinology , physical therapy , cardiology , anatomy , angiography

The muscle weakness that is exhibited poststroke is due to a multifactorial etiology involving the central nervous system and skeletal muscle changes. Insulinlike growth factor 1 (IGF-1) and IGF binding protein 3 (IGFBP-3) have been described as biomarkers of neuromuscular performance in many conditions. However, no information about these biomarkers is available for people with chronic hemiparesis.

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