Secondary Mediation and Regression Analyses of the PTClinResNet Database: Determining Causal Relationships Among the International Classification of Functioning, Disability and Health Levels for Four Physical Therapy Intervention Trials
Author(s) -
Sara J. Mulroy,
Carolee J. Winstein,
Kornelia Kulig,
George J. Beneck,
Eileen Fowler,
Sharon K. DeMuth,
Katherine J. Sullivan,
David A. Brown,
Christianne J. Lane
Publication year - 2011
Publication title -
physical therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 150
eISSN - 1538-6724
pISSN - 0031-9023
DOI - 10.2522/ptj.20110024
Subject(s) - physical therapy , international classification of functioning, disability and health , physical medicine and rehabilitation , medicine , rehabilitation , randomized controlled trial , cerebral palsy , clinical trial , mediation , low back pain , quality of life (healthcare) , stroke (engine) , nursing , mechanical engineering , alternative medicine , engineering , pathology , political science , law
Each of the 4 randomized clinical trials (RCTs) hosted by the Physical Therapy Clinical Research Network (PTClinResNet) targeted a different disability group (low back disorder in the Muscle-Specific Strength Training Effectiveness After Lumbar Microdiskectomy [MUSSEL] trial, chronic spinal cord injury in the Strengthening and Optimal Movements for Painful Shoulders in Chronic Spinal Cord Injury [STOMPS] trial, adult stroke in the Strength Training Effectiveness Post-Stroke [STEPS] trial, and pediatric cerebral palsy in the Pediatric Endurance and Limb Strengthening [PEDALS] trial for children with spastic diplegic cerebral palsy) and tested the effectiveness of a muscle-specific or functional activity-based intervention on primary outcomes that captured pain (STOMPS, MUSSEL) or locomotor function (STEPS, PEDALS).
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