Open AccessAcinetobacter baumannii: Resistance and Virulence mediated through bacterial type IV secretion system
Author(s) -
Andrés Zúñiga-Bahamon,
Fabián Tobar-Tosse,
Juan Fernando Duque Osorio,
Pedro A. Moreno
Publication year - 2017
Publication title -
revista estomatología
Language(s) - English
Resource type - Journals
eISSN - 2248-7220
pISSN - 0121-3873
DOI - 10.25100/re.v21i2.5765
Subject(s) - acinetobacter baumannii , microbiology and biotechnology , virulence , secretion , acinetobacter , biology , antibiotic resistance , bacteria , antibiotics , gene , genetics , pseudomonas aeruginosa , biochemistry
SUMMARYIntroduction: Type IV Bacterial SecretionSystems (TFSS) have a variety of biologicalfunctions such as the exchange ofgenetic material with other bacteria andvirulent translocation of DNA with itseffector proteins into host cells. A. baumanniiis a pathogen that causes infections inhumans and exhibits high rates of multidrugresistance to drugs.Objective: To relate how type IV secretionsystems is associated with patterns ofresistance and virulence in A. baumannii.Materials and Methods: Exhaustive searchin PMC (NCBI) using a set of keywordswas performed.Results: The search yielded 133 articles.Fourteen articles were analysed to determinethe bacterial secretion system and theresistant and virulence of AA. baumannii.Conclusions: Systems of bacterial typeIV secretion present in A. baumannii arecrucial in understanding the patterns ofvirulence and resistance.Key words: Pathogenicity, type four secretionsystem (T4SS), A. baumannii, virulencefactors, multidrug bacterial resistance(MDR), horizontal gene transfer (HGT).
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