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Abstrak Preeklampsia dan eklampsia merupakan penyebab utama morbiditas dan mortalitas ibu dan bayi di dunia, dimana terjadi penurunan albumin serum (hipoalbuminemia) sehingga tekanan hipovolemik intravaskular berkurang. Tujuan penelitian ini adalah untuk mengetahui hubungan kadar albumin serum dengan morbiditas dan mortalitas maternal pasien preeklampsia berat dan eklampsia. Penelitian ini bersifat analitik observasional retrospektif dilakukan dengan desain cross sectional study. Populasi penelitian adalah seluruh data rekam medis pasien preeklampsia berat dan eklampsia di RSUP Dr. M. Djamil Padang periode Januari 2012 – Desember 2012. Sampel ditetapkan dengan teknik total sampling sehingga didapatkan sampel sebanyak 133 kasus. Pengolahan data dilakukan secara komputerisasi dan analisis dengan uji chi-square. Hasil penelitian menunjukkan angka kejadian morbiditas maternal adalah 33,8%, mortalitas maternal 3,8% dan 3,8% pasien dengan hipoalbuminemia. Dari hasil analisis, tidak terdapat hubungan yang bermakna antara kadar albumin serum dengan morbiditas dan mortalitas maternal pasien preeklampsia berat dan eklampsia, dimana nilai p=1 untuk hubungan kadar albumin serum dengan morbiditas maternal dan p=0,177 untuk hubungan kadar albumin serum dengan mortalitas maternal pasien preeklampsia berat dan eklampsia (p>0,05). Kata kunci: preeklampsia berat, eklampsia, albumin serum Abstract Preeclampsia and eclampsia are major causes of maternal and fetal morbidity and mortality in the world, in which serum albumin decreases (hypoalbuminemia) so hypovolemic intravascular pressure will be reduced. The objective of this study was to determine the relation between serum albumin levels and maternal morbidity and mortality of severe preeclampsia and eclampsia patients. A retrospective observational analytical research was conducted with a cross sectional study design. The study population was the entire medical records of severe preeclampsia and eclampsia patients in RSUP Dr. M. Djamil Padang, period January 2012 – December 2012. The sample was determined by total sampling technique which obtained a sample of 133 cases. Data processing was computerized and analyzed by chi-square test. The incidence of maternal morbidity was 33.8%, maternal mortality was 3.8%, and 3.8% patients were with hypoalbuminemia. The analysis result obtained there was no significant correlation between serum albumin levels and maternal morbidity and mortality of severe preeclampsia and eclampsia patients, in which p=1 for serum albumin levels correlation with maternal morbidity and p=0.177 for serum albumin levels correlation with maternal mortality of severe preeclampsia and eclampsia patients (p>0.05). Keywords: severe preeclampsia, eclampsia, serum albumin

Hubungan Kadar Albumin Serum dengan Morbiditas dan Mortalitas Maternal Pasien Preeklampsia Berat dan Eklampsia di RSUP Dr. M. Djamil Padang