Formulasi Krim Berbahan Aktif Minyak Kapulaga (Amomum compactum Soland.) sebagai Antibakteri Staphylococcus aureus
Author(s) -
Lilis Pania Anugrah,
Laode Rijai,
Wisnu Cahyo Prabowo
Publication year - 2018
Publication title -
proceeding of mulawarman pharmaceuticals conferences
Language(s) - English
Resource type - Journals
ISSN - 2614-4778
DOI - 10.25026/mpc.v8i1.303
Subject(s) - physics , traditional medicine , food science , chemistry , medicine
Essential oils or volatile oils, it is known that Cardamom (Amomum compactum Soland.) Is one of the plants containing essential oils of cineol, terpineol and borneol. Cardamom oil functions as an antibacterial. The aim of this study was to determine the yield content of cardamom oil, cream base formula optimization, and to determine the antibacterial activity of cardamom oil. The research method used is steam distillation cardamom oil, and antibacterial testing, namely order diffusion disc method. The results showed that the yield of cardamom oil obtained from steam distillation was 4.867%. The evaluation results of cream preparations with different concentrations of stearic acid FI (8%) and FII (7%) include organoleptic (white color, distinctive oil odor, semisolid form), homogeneity, and dispersion in FI (6.3 cm) and FII (4.725 cm), pH FI (8,00) and FII (7,43) and viscosity FI (30,72842 Pa. s) and FII (61,69424 Pa. s). The results of antibacterial activity in cardamom oil, that the best concentration is 15% with clear zones of 10,883 mm. Keyword: Cardamom (Amomum compactum Soland.) And Antibacterials
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