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Adropin: A New Marker for Predicting Late Saphenous Vein Graft Disease after Coronary Artery Bypass Grafting
Author(s) -
Bora Demirçelik,
Muzaffer Çakmak,
Yunus Nazlı,
Özgül Malçok Gürel,
Nermin Akkaya,
Mustafa Çetın,
Zehra Güven Çetin,
Yusuf Selçoki,
Alparslan Kurtul,
Beyhan Eryonucu
Publication year - 2014
Publication title -
clinical and investigative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 47
eISSN - 1488-2353
pISSN - 0147-958X
DOI - 10.25011/cim.v37i5.22014
Subject(s) - medicine , occlusion , bypass grafting , cardiology , artery , vein , anastomosis , complication , surgery , coronary artery disease , pathogenesis , saphenous vein graft
Saphenous vein graft disease (SVGD), defined as an occlusion of 50% or more of the SVG excluding distal anastomotic occlusion, is an important predictor of morbidity after coronary artery bypass grafting (CABG). Late graft occlusion is a serious complication that often limits the use of the saphenous vein as a coronary bypass graft. Late graft occlusion is particularly common in old, degenerated venous grafts with advanced atherosclerotic plaques. Adropin has been implicated in the homeostatic control of metabolism. The purpose of this study was to investigate whether serum adropin levels are associated with late SVGD following CABG.

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