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Polimorfismos del TLR4 en pacientes con enfermedad de Stargardt: un estudio familiar
Author(s) -
Ramses Rosales-Díaz,
Alejandro GonzálezDe la Rosa,
Nicole Macriz-Romero,
Juan Carlos Altamirano-Vallejo,
Abril Bernardette Martínez-Rizo,
Arturo Santos,
Adolfo Daniel Rodríguez-Carrizález,
José NavarroPartida
Publication year - 2019
Publication title -
revista mexicana de oftalmología
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 6
eISSN - 2604-1227
pISSN - 0187-4519
DOI - 10.24875/rmo.m20000102
Subject(s) - medicine
Purpose: Retinal pigment epithelial cells exhibit a propensity for apoptosis in Stargardt macular dystrophy (STGD). Previously, single-nucleotide polymorphisms (SNPs) in the toll-like receptor 4 (TLR4) gene have been related to apoptosis and inflammatory response. Therefore, this study was undertaken to investigate whether TLR4 SNPs are associated with STGD in a family-based

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