Atypical MRI features involving the brain in Wilson's disease | Zendy

Muhammad Abdullah Yousaf | Zendy; Manoj Kumar | Zendy; Raghu Ramakrishnaiah | Zendy; Rudy Vanhemert | Zendy; Edgardo Angtuaco | Zendy

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Atypical MRI features involving the brain in Wilson's disease

Author(s) -

Muhammad Abdullah Yousaf,

Manoj Kumar,

Raghu Ramakrishnaiah,

Rudy Vanhemert,

Edgardo Angtuaco

Publication year - 2009

Publication title -

radiology case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.221

H-Index - 10

ISSN - 1930-0433

DOI - 10.2484/rcr.v4i3.312

Subject(s) - pons , brainstem , midbrain , wilson's disease , pathology , cerebellum , thalamus , medicine , anatomy , neuroscience , disease , central nervous system , biology , radiology

Wilson's disease is an inborn error of copper metabolism characterized by inability of the liver to excrete copper into the bile, with excessive deposition of copper primarily in the liver and in the brain. The lentiform nuclei are involved, most often followed by involvement of the thalami, the pons, midbrain, superior and inferior cerebellar peduncles, and the cerebellar nuclei. Predominant involvement of the thalami and brainstem with no significant involvement of the lentiform nuclei is not common. We present a case of Wilson's disease with minimal involvement of the lentiform nuclei, with marked lesions involving the thalami, midbrain, and pons

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