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Saliva can be used as an alternative in establishing the diagnosis, prognosis, and treatment plan. Variations in salivary concentrations can be used as biomarkers of oxidative stress. Free radicals are molecules or compounds which have unpaired electrons. Furthermore, unbalanced levels of free radicals and antioxidants can cause oxidative stress. In order to reduce free radicals, antioxidants are needed. Rambutan honey gel is a natural ingredient that has been widely used since it has many benefits and ingredients. Flavonoid is one of rambutan honey contents. Flavonoids have function as donors of hydrogen groups. The aim of this study is to see the effect of application of rambutan honey gel against malondialdehyde (MDA) saliva levels. The method used was a quasi-experimental prepost design with 30 respondents. In addition, the sampling technique used consecutive sampling. Respondents would be asked to collect saliva before and after the application of rambutan honey gel in the inferior labial oral mucosa. Salivary MDA would be calculated using TBARs spectrophotometric method. Data were analyzed using the Wilcoxon test (p <0.05). The results show that there is effect of application of rambutan honey gel against malondialdehyde (MDA) saliva levels. The conclusion is that rambutan honey gel contains antioxidants which can reduce MDA contents.

EFEK APLIKASI GEL MADU RAMBUTAN PADA MUKOSA LABIAL INFERIOR TERHADAP KADAR MALONDIALDEHID (MDA) SALIVA