
Non-secretory myeloma in young man mimicking the Gorham disease: case report and the literature review
Author(s) -
H. Ferjani,
Moalla Mariem,
Hassen Affess,
Kaouther Maatallah,
Dhia Kaffel,
Mourad Jenzri,
Wafa Hamdi
Publication year - 2022
Publication title -
romanian journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.223
H-Index - 20
eISSN - 2501-062X
pISSN - 1582-3296
DOI - 10.2478/rjim-2021-0036
Subject(s) - medicine , multiple myeloma , incidence (geometry) , rare disease , bone marrow , biopsy , plasma cell neoplasm , disease , bone disease , radiology , radiography , pathology , neoplasm , plasmacytoma , osteoporosis , physics , optics
Multiple myeloma is a neoplasm of plasma cells affecting mostly the elderly with incidence peaks between 60 and 70 years. This disease is exceedingly rare in younger people, especially in adults under 30-year-old. Non-secretory multiple myeloma accounts for 1–5% of all cases of multiple myeloma. It is also a rare condition in young adult patients, and only six cases have been reported [1]. We herein describe a rare case of non-secretory myeloma in a 22-year-old male, explaining from chest wall pain, without general manifestation. Plain radiography and CT scans revealed diffuse osteolytic lesion mimicking the Gorham disease. A bone marrow biopsy was conducted, revealing the diagnosis of myeloma.