An investigation of secondary anti-D immunisation among phenotypically RhD-negative individuals in the Chinese population.
Author(s) -
Qingping Wang,
Guangtao Dong,
Xuedong Wang,
Juan Gu,
Li Zheng,
Aihua Sun,
ChaoPeng Shao,
Zhao-Lin Pan,
Lihua Huang,
Wei-Xing Xie,
Guangming Sun,
Jianjiang Chen,
Pei Hao,
Xiao Yang,
Ping-nan Shan
Publication year - 2014
Publication title -
pubmed
Language(s) - English
Resource type - Journals
eISSN - 2385-2070
pISSN - 1723-2007
DOI - 10.2450/2013.0184-12
Subject(s) - medicine , incidence (geometry) , context (archaeology) , immunology , pregnancy , isoantibodies , population , pediatrics , antibody , biology , environmental health , genetics , paleontology , physics , optics
Despite the introduction of anti-D prophylaxis into clinical practice, RhD alloimmunisation remains a problem, particularly in the context of transfusions and pregnancy-induced alloimmunisation. The incidence of RhD alloimmunisation among phenotypically RhD-negative individuals is unknown in most countries. We investigated RhD alloimmmunisation in RhD-negative pregnant women and transfusion recipients in south-east China in order to optimise the prevention of this phenomenon.
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