The NMR Study and Antimicrobial Activity of Some Schiff Bases Derived From Sulphonamide Drug | Zendy

Wasfi Aboud | Zendy; Harith Y. Mahmood | Zendy; Rasha M. Othman‎ | Zendy; Wasan Moaed Shaker | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The NMR Study and Antimicrobial Activity of Some Schiff Bases Derived From Sulphonamide Drug

Author(s) -

Wasfi Aboud,

Harith Y. Mahmood,

Rasha M. Othman‎,

Wasan Moaed Shaker

Publication year - 2016

Publication title -

journal of advances in chemistry

Language(s) - English

Resource type - Journals

ISSN - 2321-807X

DOI - 10.24297/jac.v12i2.2157

Subject(s) - aspergillus niger , chemistry , antimicrobial , schiff base , candida tropicalis , candida krusei , antibacterial activity , bacillus cereus , benzaldehyde , heteronuclear single quantum coherence spectroscopy , escherichia coli , staphylococcus aureus , candida albicans , carbon 13 nmr , klebsiella pneumonia , proton nmr , sulfonamide , organic chemistry , nuclear chemistry , microbiology and biotechnology , stereochemistry , nuclear magnetic resonance spectroscopy , bacteria , biochemistry , yeast , biology , genetics , gene , catalysis

Some Schiff base compounds derived from sulfonamide drug were synthesized by reaction of 4-aminobenzenesulfonamide with aromatic aldehydes (2-hydroxy-1-naphthaldehyde, 3,4-dihydroxybenzaldehyde and 2-hydroxy benzaldehyde) in good yields. Characterization of synthesized compound was carried by elemental analysis, IR, 1H,13C, HSQC and HMBC- NMR spectroscopy. The synthesized compounds were screened for their antibacterial activity against Staphylococcus aureus, Streptococcus sp., Bacillus subtillus, Escherichia coli and Klebsiella pneumonia. Additionally, the compounds were tested for antifungicidal activity against Candida krusei, Candida tropicalis, Aspergillus fumigates and Aspergillus niger.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research