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Synthesis and Biological activity of 1,3-Thiazolylidenehydrazinylidene ethylpyridiniumbromide monohydrate, 1,3-Thiazolylidenehydraziniumbromide and 1,3-Thiazolylidenehydrazine derivatives
Author(s) -
Alaa A. Hassan,
Shaaban K. Mohamed,
Nasr K. Mohamed,
Kamal M. ElShaieb,
Ahmed T. AbdelAziz,
Marwa Rageh Abdel Rahman
Publication year - 2015
Publication title -
journal of advances in chemistry
Language(s) - English
Resource type - Journals
ISSN - 2321-807X
DOI - 10.24297/jac.v11i3.863
Subject(s) - bromide , chemistry , carbon 13 nmr , combinatorial chemistry , proton nmr , medicinal chemistry , stereochemistry , organic chemistry
1,3-Thiazolylidenehydrazinylidene ethylpyridinium bromide monohydrate, 1,3-thiazolylidenehydrazinium bromide and 1,3-thiazolylidenehydrazine derivatives were synthesized by heterocyclization of 2-(1-substituted ethylidene) hydrazinecarbothioamides, characterized and screened for their anti-bacterial activities. The structures of synthesized compounds were established by spectroscopic (IR, 1H, 13C-NMR, Mass) and X-ray analyses.

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