Inhibition Activity of Nanoparticles Zno and Tio2 against Bacterial Species Isolated from Different Infections

Different species of bacteria(Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa,Proteus spp.,Klebsiella spp., Staphylococcus epidermidis)were isolated from urinary tract infections,burn infections and wound infections from inpateints and outpateints of Azadi educational hospital and public hospital of Kirkuk.The diagnosis of isolates was based on phenotypic,microscopic and biochemical tests.Inhibition activity of nanoparticles ZnONPs and TiO2NPs were tested against bacterial isolates after determined the minimum inhibition concentration(MIC).The results showed that the MIC was at (2mg/ml) against bacterial species,so the results also showed the variation of nanoparticles in inhibition activities.The higher diameter of inhibition regions of TiO2NPs was against E.coli and S.epidermidis which isolated from burn and wound infections respectively at (13) mm,and the maximum of inhibition activity of ZnONPs was against S.epidermidis which isolated from urinary tract infections.The results showed the synergism effect between nanoparticles and antibiotics(Azithromycin,Ciprofloxacin and Ceftriaxone).