THE USE OF ANTIMICROBIAL PHOTODYNAMIC THERAPY MEDIATED BY MC540 IN THE INFECTED WOUND MODEL

28 Skin is the body’s natural physical barrier and the first line of defense against pathogens. Damaged skin can end up getting infected. In turn, infection can delay wound healing, compromise a person’s general health and even increase the risk of death. Antibiotics once revolutionized the therapy of infections, but today the growing incidence of resistant bacteria compels the search for new alternatives to the conventional management of localized infections. One of the promising solutions here is photodynamic therapy (PDT) that is normally used in cancer treatment [1–3] but has been recently proposed to combat bacterial infections [4–7]. Antimicrobial PDT relies on the use of photosensitizers (PS), non-toxic dyes that can be activated Т. А. Шмиголь , К. А. Собянин, М. В. Прусак-Глотов, С. П. Щелыкалина, Е. В. Невежин, С. А. Ермолаева, В. В. Негребецкий ПРИМЕНЕНИЕ АНТИМИКРОБНОЙ ФОТОДИНАМИЧЕСКОЙ ТЕРАПИИ НА ОСНОВЕ МЦ540 К МОДЕЛИ РАНЕВОЙ ИНФЕКЦИИ