A new marker for the prediction of mean platelet volume, placenta previa and placental invasion anomalies

Objective: The aim of this study is to evaluate the relationship between some parameters of complete blood count and placenta previa and placental invasion anomalies. Methods: In this study, 70 cases with placenta previa and 70 control cases who admitted to the Department of Obstetrics and Gynecology of Mustafa Kemal University between September 2015 and December 2016 were reviewed retrospectively. The sociodemographic data and the numbers of previous cesarean section of the patients were recorded. Before the cesarean section, the counts of preoperative lymphocyte, neutrophil and platelet, mean platelet volume (MPV), neutrophil/lymphocyte rate, platelet/lymphocyte rate, and hemoglobin and hematocrit values were recorded. It was analyzed whether these parameters were able to predict placenta previa and placental invasion anomalies or not. Results: There was no difference between two groups in terms of sociodemographic (age, gravida, parity, living fetus and the number of previous cesarean section) data. The week of gestation during delivery and birth weight were significantly low in placenta previa group. Postoperative hemoglobin and hematocrit values were also significantly low in previa group. Considering the complete blood parameters, MPV was significantly low in previa group (p=0.042). Placental invasion anomaly was confirmed histopathologically in 24 of 27 cases in previa group who underwent cesarean hysterectomy. When the group with invasion anomaly was compared to the control group, MPV was also significantly low (p=0.047). Conclusion: In addition to the ultrasound images, simple blood count parameters can be used to confirm placenta previa and placental invasion anomalies in particular. Among these parameters, MPV seems to be the most potent predictor.