Evaluating 101 cases with the anomaly of fetal central nervous system

Objective: We aimed to determine structural and chromosomal malformations in cases with the anomaly of fetal central nervous system and to evaluate the prognoses of these pregnancies. Methods: Between 2010 and 2015, 101 cases found to have the anomaly of fetal nervous system were investigated retrospectively. Information such as maternal age, number of gestation, number abortion, week of gestation during diagnosis, anomalies found in ultrasonography, chromosome analysis results and council decision were evaluated. Results: Cranial anomalies were found only in 26.7% of pregnancies while extracranial anomalies were found in 51.5% of them and abnormal karyotype was found in 11.9% of them. The most common anomaly of central nervous system was ventriculomegaly (51.5%). 68.3% of the pregnancies were terminated by council decision. Extremity anomalies were the most common type of extracranial anomalies (23.8%). Conclusion: It is necessary to determine concurrent structural and chromosomal anomalies in order to determine prognoses and management of pregnancies with the anomaly of fetal central nervous system.