Neurofibromatosis type 1 case with cerebral involvement complicating pregnancy

Objective: Neurofibromatosis-1 is a disease with an autosomal dominant inheritance pattern and heterogenous clinical presentation. Although it is not rare, its diagnosis may be overlooked except the cases evaluated by the specialists from related disciplines. In this report, we aimed to discuss the progress and complications of the disease during pregnancy over a case diagnosed with neurofibromatosis-1 during pregnancy. Case: Twenty-eight-year-old case who was pregnant for 30 weeks admitted with hypertension, proteinuria and convulsions. The patient delivered with the diagnosis of preeclampsia/eclampsia was established the diagnosis of neurofibromatosis-1 during postoperative period. Conclusion: Neurofibromatosis-1 during pregnancy may cause serious problems with the rapid growth of neurofibromas, changing characteristics or the addition of new ones. To predict possible complications that may develop and to minimize them, neurofibromatosis-1 cases should be managed with an experienced and multidisciplinary team approach.