Microwave-assisted Synthesis of Some New N, N`-Bis-[(2-hydroxy- napthalene-1-yl) Substituted Phenyl-methyl] 4,4`-diaminodiphenyl- Sulphone
Author(s) -
Dalia A. Abdul,
Faiq H. S. Hussain
Publication year - 2019
Publication title -
eurasian journal of science and engineering
Language(s) - English
Resource type - Journals
eISSN - 2414-5629
pISSN - 2414-5602
DOI - 10.23918/eajse.v4i4p48
Subject(s) - chemistry , microwave , medicinal chemistry , combinatorial chemistry , organic chemistry , engineering , telecommunications
An efficient and easy approach to N,N`-Bis-[(2-hydroxy-napthalene-1-yl) substituted phenylmethyl] 4,4`-diamine diphenyl sulphone derivatives is presented in this study. The products can be obtained both through the traditional method and via the microwave assisted protocol from the condensation of 4,4`-diamine diphenyl sulphone, benzaldehydes derivatives and β-naphthol. The characterization of the newly provided compounds elucidated by spectral methods: FT-IR, 1 H-NMR, 13 C-NMR, and Mass spectral data. Finally, the bis-Bestti bases have been screened for antimicrobial and antifungal activities. Keyword: Bis-Betti Base, 2-Naphthol, Microwave, One-Pot Reaction, Aromatic Aldehydes.
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