Adherencia y biocompatibilidad in vitro de recubrimientos de fosfato de calcio-titanio de calcio obtenidos por magnetrón sputtering para aplicaciones ortopédicas

Hydroxyapatite coatings have been used for manyyears in hip prosthesis stems. However, it has been observedthat the coatings detaches leading to the loosening of theprosthesis due to their mechanical properties did not meetthe requirements. Since calcium titanate has been proposedas a coating for biomedical applications due to its good invitro biocompatibility and osteoconductivity, adherenceand elastic modulus of calcium phosphate-calcium titanatecomposite coatings were assessed by means of scratch test(ASTM C1624-05) and nanoindentation test (ASTM E2546-07). In vitro biomedical properties such as genotoxicityand hemolysis were evaluated also (ASTM F748-06).100% calcium phosphate (CP) coating was composed of amixture of tricalcium and tetracalcium phosphate. Calciumtitanate (CT) was added to the coatings, by modifyinga Ca10(PO4)6(OH)2- 2xOx□x target, in 25, 50 and 75 volumepercentages. For comparison purposes, 100% TC coatingswere also obtained. It was found that adherence increasesas added 25% of one material of another rising a maximumvalue in 50-50 composite coating. Besides, the coatingswere not genotoxic and not hemolytic.