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Comparison of Bariatric Surgical Procedures for Diabetes Remission: Efficacy and Mechanisms
Author(s) -
Marion L. Vetter,
Scott Ritter,
Thomas A. Wadden,
David B. Sarwer
Publication year - 2012
Publication title -
diabetes spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.716
H-Index - 31
eISSN - 1944-7353
pISSN - 1040-9165
DOI - 10.2337/diaspect.25.4.200
Subject(s) - medicine , weight loss , diabetes mellitus , hormone , glucose homeostasis , body weight , surgery , obesity , endocrinology , insulin resistance
Bariatric surgery induces a mean weight loss of 15-30% of initial body weight (depending on the procedure), as well as a 45-95% rate of diabetes remission. Procedures that induce greater weight loss are associated with higher rates of diabetes remission. Improvements in glucose homeostasis after bariatric surgery are likely mediated by a combination of caloric restriction (followed by weight loss) and the effects of altered gut anatomy on the secretion of glucoregulatory gut hormones.

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