Hypoglycemia in Type 1 and Type 2 Diabetes: Physiology, Pathophysiology,and Management
Author(s) -
Vanessa Jones Briscoe,
Stephen N. Davis
Publication year - 2006
Publication title -
clinical diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.931
H-Index - 37
eISSN - 1945-4953
pISSN - 0891-8929
DOI - 10.2337/diaclin.24.3.115
Subject(s) - hypoglycemia , glycemic , medicine , limiting , type 2 diabetes , type 1 diabetes , pathophysiology , intensive care medicine , diabetes mellitus , incidence (geometry) , endocrinology , mechanical engineering , physics , optics , engineering
IN BRIEF The threat and incidence of hypoglycemia is the major limiting factor inintensive glycemic control for both type 1 and type 2 diabetes. This articlereviews the physiology of the normal counterregulatory responses tohypoglycemia and the deficient counterregulatory defenses that occur inpatients with diabetes. Treatment paradigms for establishing good glycemiccontrol while limiting hypoglycemia are also discussed.
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