Elevated Liver Function Tests in Type 2 Diabetes | Zendy

Elizabeth H. Harris | Zendy

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Elevated Liver Function Tests in Type 2 Diabetes

Author(s) -

Elizabeth H. Harris

Publication year - 2005

Publication title -

clinical diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.931

H-Index - 37

eISSN - 1945-4953

pISSN - 0891-8929

DOI - 10.2337/diaclin.23.3.115

Subject(s) - medicine , contraindication , type 2 diabetes , insulin resistance , liver function , diabetes mellitus , alanine aminotransferase , liver function tests , hepatic function , gastroenterology , endocrinology , insulin , pathology , alternative medicine

IN BRIEF Individuals with type 2 diabetes have a higher incidence of liver functiontest abnormalities than individuals who do not have diabetes. Mild chronicelevations of transaminases often reflect underlying insulin resistance.Elevation of transaminases within three times the upper limits of normal isnot a contraindication for starting oral antidiabetic or lipid-modifyingtherapy. In contrast, antidiabetic agents have generally been shown todecrease alanine aminotransferase levels as tighter blood glucose levels areachieved.

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