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Comparison of the [13C]Glucose Breath Test to the Hyperinsulinemic-Euglycemic Clamp When Determining Insulin Resistance
Author(s) -
Richard Lewanczuk,
Breay W. Paty,
Ellen L. Toth
Publication year - 2004
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/diacare.27.2.441
Subject(s) - clamp , medicine , insulin resistance , glucose clamp technique , endocrinology , insulin , diabetes mellitus , glucose uptake , glucose tolerance test , carbohydrate metabolism , insulin sensitivity , quantitative insulin sensitivity check index , type 2 diabetes , breath test , mechanical engineering , helicobacter pylori , clamping , engineering
With increasing emphasis on the recognition of the metabolic syndrome and early type 2 diabetes, a clinically useful measure of insulin resistance is desirable. The purpose of this study was to evaluate whether an index of glucose metabolism, as measured by (13)CO(2) generation from ingested [(13)C]glucose, would correlate with indexes from the hyperinsulinemic-euglycemic clamp.

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