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Once-Weekly Exenatide in Youth With Type 2 Diabetes
Author(s) -
William V. Tamborlane,
Raafat Bishai,
David H. Geller,
Naim Shehadeh,
Dalia AlAbdulrazzaq,
Evelina Mánica Vazquez,
Eva Karoly,
Tünde Troja,
Orlando Doehring,
Debra Carter,
John T. Monyak,
C. David Sjöström
Publication year - 2022
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc21-2275
Subject(s) - exenatide , medicine , glycated hemoglobin , liraglutide , type 2 diabetes , placebo , metformin , diabetes mellitus , adverse effect , endocrinology , insulin , gastroenterology , alternative medicine , pathology
Approved treatments for type 2 diabetes in pediatric patients include metformin, liraglutide, and insulin. However, approximately one-half of the youth fail metformin monotherapy within 1 year, insulin therapy is associated with challenges, and liraglutide requires daily injections. Consequently, the efficacy and safety of once-weekly injections of exenatide for the treatment of youth with type 2 diabetes was evaluated.

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