The Gut Microbiome Composition Is Altered in Long-standing Type 1 Diabetes and Associates With Glycemic Control and Disease-Related Complications
Author(s) -
Julia I. P. van Heck,
Ranko Gaćeša,
Rinke Stienstra,
Jingyuan Fu,
Alexandra Zhernakova,
Hermie J. M. Harmsen,
Rinse K. Weersma,
Leo A. B. Joosten,
Cees J. Tack
Publication year - 2022
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc21-2225
Subject(s) - microbiome , type 2 diabetes , diabetes mellitus , medicine , glycemic , gut flora , type 1 diabetes , macrovascular disease , metagenomics , disease , nephropathy , physiology , immunology , bioinformatics , biology , endocrinology , genetics , gene
People with type 1 diabetes are at risk for developing micro- and macrovascular complications. Little is known about the gut microbiome in long-standing type 1 diabetes. We explored differences in the gut microbiome of participants with type 1 diabetes compared with healthy control subjects and associated the gut microbiome with diabetes-related complications.
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