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Changes in Glucose Metabolism and Glycemic Status With Once-Weekly Subcutaneous Semaglutide 2.4 mg Among Participants With Prediabetes in the STEP Program
Author(s) -
Leigh Perreault,
Melanie J. Davies,
Juan P. Frías,
Peter Nørkjær Laursen,
Ildiko Lingvay,
Sriram Machineni,
Anette Varbo,
John Wilding,
Signe Olrik Rytter Wallenstein,
Carel W. le Roux
Publication year - 2022
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc21-1785
Subject(s) - prediabetes , medicine , semaglutide , diabetes mellitus , glycemic , endocrinology , carbohydrate metabolism , type 2 diabetes , liraglutide
This analysis of 3,375 adults with overweight/obesity across the Semaglutide Treatment Effect in People with obesity (STEP) 1, 3, and 4 trials evaluated whether more participants with prediabetes had normoglycemia after 68 weeks' treatment with once-weekly semaglutide 2.4 mg plus lifestyle intervention versus placebo and assessed changes in glucose metabolism in participants with prediabetes.

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