Efficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study | Zendy

Priyathama Vellanki | Zendy; Saumeth Cardona | Zendy; Rodolfo J. Galindo | Zendy; Maria A. Urrutia | Zendy; Francisco J. Pasquel | Zendy; Georgia M. Davis | Zendy; Maya Fayfman | Zendy; Alexandra L. Migdal | Zendy; Limin Peng | Zendy; Guillermo E. Umpierrez | Zendy

Open Access

Efficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study

Author(s) -

Priyathama Vellanki,

Saumeth Cardona,

Rodolfo J. Galindo,

Maria A. Urrutia,

Francisco J. Pasquel,

Georgia M. Davis,

Maya Fayfman,

Alexandra L. Migdal,

Limin Peng,

Guillermo E. Umpierrez

Publication year - 2022

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc21-1606

Subject(s) - medicine , insulin , bedtime , hypoglycemia , diabetes mellitus , glycemic , type 2 diabetes , bolus (digestion) , intensive care , endocrinology , randomized controlled trial , gastroenterology , intensive care medicine

Administration of supplemental sliding scale insulin for correction of hyperglycemia in non-intensive care unit (ICU) patients with type 2 diabetes is frequently used with basal-bolus insulin regimens. In this noninferiority randomized controlled trial we tested whether glycemic control is similar with and without aggressive sliding scale insulin treatment before meals and bedtime in patients treated with basal-bolus insulin regimens.

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