Heterogeneity of Type 1 Diabetes at Diagnosis Supports Existence of Age-Related Endotypes | Zendy

Anna Parviainen | Zendy; Taina Härkönen | Zendy; Jorma Ilonen | Zendy; Anna But | Zendy; Mikael Knip | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Heterogeneity of Type 1 Diabetes at Diagnosis Supports Existence of Age-Related Endotypes

Author(s) -

Anna Parviainen,

Taina Härkönen,

Jorma Ilonen,

Anna But,

Mikael Knip

Publication year - 2022

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc21-1251

Subject(s) - medicine , autoantibody , diabetes mellitus , type 1 diabetes , disease , ketoacidosis , human leukocyte antigen , type 2 diabetes , diabetic ketoacidosis , age of onset , pediatrics , immunology , endocrinology , antigen , antibody

Previous findings suggest that there are age-related endotypes of type 1 diabetes with different underlying etiopathological mechanisms in those diagnosed at age <7 years compared with those diagnosed at age ≥13 years. We set out to explore whether variation in demographic, clinical, autoimmune, and genetic characteristics of children and adolescents with newly diagnosed type 1 diabetes support the existence of these proposed endotypes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research