Strict Preanalytical Oral Glucose Tolerance Test Blood Sample Handling Is Essential for Diagnosing Gestational Diabetes Mellitus | Zendy

Julia M. Potter | Zendy; Peter E. Hickman | Zendy; Carmen Oakman | Zendy; Catherine Woods | Zendy; Christopher J. Nolan | Zendy

Open Access

Strict Preanalytical Oral Glucose Tolerance Test Blood Sample Handling Is Essential for Diagnosing Gestational Diabetes Mellitus

Author(s) -

Julia M. Potter,

Peter E. Hickman,

Carmen Oakman,

Catherine Woods,

Christopher J. Nolan

Publication year - 2020

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc20-0304

Subject(s) - medicine , centrifugation , gestational diabetes , diabetes mellitus , pregnancy , obstetrics , endocrinology , gestation , chromatography , chemistry , biology , genetics

Preanalytical processing of blood samples can affect plasma glucose measurement because ongoing glycolysis by cells prior to centrifugation can lower its concentration. In June 2017, ACT Pathology changed the processing of oral glucose tolerance test (OGTT) blood samples for pregnant women from a delayed to an early centrifugation protocol. The effect of this change on the rate of gestational diabetes mellitus (GDM) diagnosis was determined.

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